The event is to take place April 30 at the Washington Hilton hotel in Washington.
Meyers, who served as host of the 2010 ESPY Awards on ESPN in July, is currently in his 10th season on "SNL" -- his fifth season as head writer and his fifth season as anchor of the show's "Weekend Update" faux-news segment.
A graduate of Northwestern University, he studied and performed at ImprovOlympic before moving on to the Boom Chicago Theater in Amsterdam, Holland.
"We're very excited. Seth is a very smart, very sharp, and very funny observer of the political scene, and we're looking forward to seeing him on April 30," David Jackson of USA TODAY, president of the WHCA, said in a statement Wednesday.