Reese, 79, is an award-winning actress and singer, a Detroit native and an ordained minister in Los Angeles.
She will appear in an episode of "Detroit 1-8-7" set to air Dec. 7.
"Ms. Reese will portray Lorraine Henderson, an urban, working-class mother in her 70s, whose son's body is found in an abandoned fallout shelter," ABC said in a synopsis of the episode. "A young man when he was murdered, Richard Henderson was believed missing since 1967. Reese's casting reflects the producers' continuing effort to showcase Detroit talent."
Wisconsin business offering 'therapeutic cuddling' forced to close
Reindeer recovered after escaping from Santa during lighting ceremony