The supernatural drama is scheduled to end its six-season run May 23.
Following the finale, Kimmel is to interview the show's stars and producers in an hourlong special.
"'Jimmy Kimmel Live: Aloha to Lost' is the culmination of a six-year-long relationship between 'Lost' and 'Jimmy Kimmel Live,'" ABC said in a news release Friday. "Each Tuesday night, Kimmel discusses the show and features 'Secrets of "Lost' -- comedic 'insight' into the mysteries of the island from (cast members) Evangeline Lilly, Michael Emerson, Jorge Garcia, Daniel Dae Kim, Elizabeth Mitchell and more ... . For any fan of 'Lost,' this event is not to be missed. After the secrets of the island are revealed, go back in time one last time with Jimmy Kimmel."
The "Lost" finale is to air Sunday, May 23 from 9-11 p.m. ET on ABC. "Jimmy Kimmel Live: Aloha to Lost" is to air immediately after the local news from 11:35 p.m.-12:35 a.m. ET, the network said.