Kudrow is to be a guest star on the episode slated to air Jan. 6.
"Despite fearing the meanest and most unrelenting dermatologist in town, Dr. Amy Evans (played by Kudrow), Jules and Ellie are willing to endure the harsh ridicule and wrath for an appointment with the best in the business," the network said in a news release Monday. "But when Jules learns Dr. Evans is seeing Bobby, she's determined to stand up to her and protect him."
Cox plays Jules, Christa Miller plays Ellie and Brian Van Holt plays Bobby.
Cox and Kudrow co-starred in TV's "Friends" from 1994 through 2004.
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