Arquette's film credits include "Baby It's You," "Desperately Seeking Susan" and "Pulp Fiction."
ABC said she is to play New York art maven Greta Noa in the Nov. 18 episode of "Eastwick."
"Thrilled when Darryl arranges an art show for her work at his mansion -- and invites New York art maven Greta Noa -- Roxie forgets that his motives might be less than pure," the network said in a news release. "Joanna turns to her power to get her life back on track, but swiftly discovers that every action, magical or otherwise, has its consequences. And Kat, still unsure about how to move on from Ray, shies away from a budding romance with Will."
The show stars Jon Bernthal as Ray, Jaime Ray Newman as Kat, Lindsay Price as Joanna, Rebecca Romijn as Roxie, Johann Urb as Will and Paul Gross as Darryl.
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