The late-night series is slated to debut Nov. 9, and will run weeknights from Monday through Thursday.
Also slated to appear on "Lopez Tonight" in its first few weeks on the air are Sandra Bullock, Ray Romano, Jamie Foxx, Jessica Alba, Charlie Sheen, Queen Latifah, Marc Anthony, Ted Danson, Andy Garcia, Larry David, Taylor Lautner, Oscar de la Hoya, Floyd Mayweather, Kelly Osbourne, Eva Mendes, Arsenio Hall and Kathy Griffin.
Additional guests will be announced in the weeks ahead, TBS said.
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