The former lead singer of The Nolans was first diagnosed with the disease in 2010.
"Bernie passed away peacefully this morning with all of her family around her," a representative for her family told the BBC Thursday. "The entire family are devastated to have lost beloved Bernie, a wonderful wife, adoring mother and loving sister, she is irreplaceable."
Nolan was also known for her acting roles on the TV shows "The Bill" and "Brookside."
Notable deaths of 2014 [PHOTOS]