But the 40-year-old "Iron Man 3" romantic love interest says she doesn't always look glamorous.
"Around the house, I'm in jeans and a T-shirt. I don't really wear makeup," she tells People in the issue to hit newsstands Friday.
That's how Paltrow's children, Apple, 8, and Moses, 7, see her, she says. "That's what they're used to."
As for her husband, 36-year-old Chris Martin of the British rock group Coldplay, "He'll make a joke about [how she looks]," she says.
"If I've gotten fully dressed up, he'll be like: 'Oh, wow! You're Gwyneth Paltrow!' Because he's used to seeing me in like baggy shorts and frizzy hair," says Paltrow, who is also the face of American fashion brand Coach and stars in the upcoming Spanish film "33 Dias" as Pablo Picasso's French lover Dora Maar. Antonio Banderas plays painter-sculptor Picasso.
Paltrow -- who won an Oscar for Best Actress in the 1998 British comedy-drama "Shakespeare in Love" -- says exercise plays is key to keeping her looking young and energetic.
"It makes me look younger and feel strong," she tells People. "When I first started, I thought: 'I'll never be good at this. This is a nightmare!' But now it's like brushing my teeth, I just do it."
Among the other celebrities on this year's 100 Most Beautiful People list are actresses Jennifer Lawrence, Halle Berry, Drew Barrymore, Kerry Washington, Jane Fonda, Amanda Seyfried and Zooey Deschanel and recording artists Kelly Rowland and Pink.
Celebrity Families of 2014 [PHOTOS]
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