Tickets go on sale Dec. 14.
The "Fleetwood Mac Live 2013" arena tour will include stops in Philadelphia, New York, Boston, Chicago and Los Angeles.
The Rock and Roll Hall of Fame inductees last took their show on the road in 2009 with the sold-out "Unleashed" concert tour, Live Nation said.
The new tour also marks the 35th anniversary of the release of their classic "Rumours" album, which has sold more than 40 million copies.
"Having started Fleetwood Mac with John McVie in 1967, it has always been so gratifying that despite the various incarnations, the band has survived. Throughout the years, though, the one thing that has remained constant is our fans. I am looking forward to getting back behind the kit, reconnecting with the fans and sharing the stage with my fellow band members," Mick Fleetwood said in a statement Monday.
"After spending four days at Lindsey's house working on music and one really fun day doing a crazy photo session, I am quite excited about next year. Everything seems to be falling into place. 2013 looks like the year of Fleetwood Mac," Stevie Nicks said.