The rapper shared awards for Best Hip Hop Video, Best Collaboration, Best Featured Verse and Viewers' Choice for "Look At Me Now," his song with Chris Brown and Busta Rhymes.
Nicki Minaj was named MVP of the Year and Kanye West's "My Beautiful Dark Twisted Fantasy" won the title of CD of the Year.
Mike Epps served as host of the show, which featured appearances by DMX, Swizz Beatz, Big Sean, Roscoe Dash, Rick Ross, Wale, Meek Mill, El Debarge, Wiz Khalifa, Heavy D and Tyrese.
LL COOL J was honored as the 2011 recipient of the I Am Hip Hop Icon Award.
Costly malfunction causes beer flood at Boston-area brewery
Megyn Kelly: Santa Claus and Jesus are both white men