The Seattle Times said the show will run for two years and include previously unseen artwork by Kurt Cobain, the late front man for the 1990s grunge band, as well as handwritten lyrics for the group's songs and the first guitar Cobain destroyed onstage.
Photographs and other memorabilia, much of which comes from the private collection of Nirvana bass player Krist Novoselic, will also be on display, the newspaper said.
"I've been able to access a lot of material that no one has seen before," EMP senior curator Jacob McMurray told the Times.
McMurray added that Cobain's wife, rocker Courtney Love -- who controls the Cobain estate -- has also been "in the loop through the whole business," as has Nirvana drummer Dave Grohl.
Notable deaths of 2014 [PHOTOS]