The film is set in 1970s Los Angeles, and follows hired leg-breaker Jackson Healy (Crowe) and private eye Holland March (Gosling) as they attempt to find a missing girl. The pair also investigate the seemingly unrelated death of a porn star, but come to find the two cases may be intertwined.
Shane Black (Kiss Kiss Bang Bang, Iron Man 3) will direct, with Joel Silver of Silver Pictures as producer. Hal Sadoff and Michael Malone will executive produce.
"Ever since we did Kiss Kiss Bang Bang, I've been eager to work with Shane again, and with this film we made it happen," Silver said in a statement. "It's a terrific script written in Shane's great cinematic voice. With Russell and Ryan on board, I know we're in for another wild ride."
The Nice Guys is scheduled for release June 17, 2016. Crowe will next appear in The Water Diviner, and Gosling is scheduled for an untitled Terrence Malick project in 2015.