The 40-year-old Scott Pilgrim vs. the World director released a joint statement with Marvel Studios on Friday.
"The studio and director have parted ways on ANT-MAN due to differences in their vision of the film. The decision to move on is amicable and does not impact the release date on July 17, 2015. A new director will be announced shortly."
Ant-Man is the superhero persona of character Henry Pym, a scientist who invents a substance that allows him to dramatically change his size. Actor Paul Rudd will star as Ant-Man in the new film.
Evangeline Lilly, Corey Stoll, Michael Douglas and Michael Peña also appear in the movie. Ant-Man debuts in theaters next summer.