The debut feature of director-writer Richard Bates Jr. also features performances by Traci Lords, Ariel Winter, Roger Bart, Jeremy Sumpter, Malcolm McDowell, Matthew Gray Gubler, Marlee Matlin, Ray Wise and John Waters.
The movie had its world premiere at the Sundance Film Festival last month.
"We are pleased to be adding 'Excision' to our slate this year," Kevin Kasha, executive vice president of acquisitions and co-productions for Anchor Bay Films, said in a statement. "It has an amazing cast and we know Anchor Bay fans will love it."
"I have been influenced my entire life by the films which Anchor Bay has brought to audiences. I could not be more excited that they have chosen to take my film out in North America," said Bates.