The as-yet-untitled film is being shot at various locations on the East Coast of the United States. It stars Robert De Niro, Paul Dano, Dale Dickey, Lili Taylor, Olivia Thirlby and Julianne Moore.
Focus Chief Executive Officer James Schamus made the announcement regarding the start of production Tuesday.
The film tells the story of a young writer, who takes a job at a homeless shelter where one night he discovers his long-absent father, Jonathan, seeking a bed. Moore portrays the writer's mother, Jody, and Thirlby portrays Denise, a worker at the shelter, Focus said in a synopsis.
"Nick's memoir was emotional, ruefully funny, and powerfully moving. Paul's movie looks to honor Nick's experiences -- and his father's," Schamus said in a statement. "We are privileged to be working with these filmmakers and talent to tell this story."
"I've been working on this script for seven years, gone through 30 drafts, and I feel extremely lucky to be making this draft, with this cast, at this studio," Weitz added.
Weitz's film credits include "About a Boy," "In Good Company" and "American Dreamz."