The original 3D project is slated for release in March 2013.
Mark Dindal is the film's director, and Melissa Cobb and Teresa Cheng are serving as producers.
"We are proud to have assembled a world-class creative team of filmmakers and artists -- all of whom have vast experience on both computer-generated and traditionally animated films -- who is already well along in the production of 'Me and My Shadow,'" Bill Damaschke, co-president of production for DreamWorks Animation, said in a statement Friday. "Together, we are embarking on an exciting goal to break new creative ground at DreamWorks Animation by combining the time-honored tradition of hand-drawn animation with the magical sophistication of CG characters and worlds in ways that have never been experienced by audiences before."
"Me and My Shadow" tells the story of Shadow Stan, an extremely frustrated shadow who yearns for a dynamic life but happens to be stuck with Stanley Grubb, the world's most boring human. Finally pushed to the brink, Shadow Stan breaks the singular rule of the Shadow World -- "They lead, we follow" -- and takes control of Stanley, DreamWorks said in a synopsis.
There's no word on casting yet.