Jean-Jacques Mantello and Richard Gabai are to co-direct the movie, which is to be released at IMAX 3D and IMAX 2D theaters in spring 2012.
Lloyd is best known for his roles in the "Back to the Future" time-travel comedy film trilogy and TV's "Taxi."
"Time, the Fourth Dimension" tells the story of an eccentric professor, played by Lloyd, and his lab assistant as they explore and explain the various dimensions that make up our world while focusing on the extraordinary and misunderstood fourth dimension: space-time," the film's producers said in a news release.
"I am very excited about this project and am eager to start shooting this 'edutainment' film in 3D in November," Lloyd said in a statement. "'Time, the 4th Dimension' will be a one-of-a-kind celebration of science that will allow audiences to better understand the concept of time and how we relate to it in modern day society."
"We are thrilled to have such a gifted actor and charismatic personality as Christopher Lloyd lend his talent to this unique project, which celebrates science through entertainment," said Francois Mantello, chairman and chief executive officer of 3D Entertainment Films.
"Principal photography using state-of-the-art 3D cameras will begin in Los Angeles-area studios this November," said directors Jean-Jacques Mantello and Richard Gabai. "This film will embrace a variety of 3D filmmaking techniques, including stunning special effects, computer-generated images as well as time-lapse and high-speed photography. It is sure to delight audiences of all ages when shown on the world's largest IMAX theater screens."