Newcomer Hemsworth plays the title character in the film, while Hopkins portrays his father, Odin.
"I am having the time of my life making 'Thor' with Ken and Chris. They have made every day immensely fun and collaborative and we're all puzzled that someone would fabricate a story suggesting otherwise," Hopkins said Friday in a statement issued to E! News. "I'm proud to say that 'Thor' has been one of the great experiences of my career."
Hopkins is best known for his work in "The Silence of the Lambs," its prequel "Red Dragon" and its sequel "Hannibal," as well as the films "Shadowlands," "Howard's End" and "Remains of the Day."