The Oscar-winning star of The Miracle Worker died early Tuesday of sepsis from a ruptured intestine. She was 69.
"This morning, our beloved wife, mother, grandmother, matriarch and the exquisite artist, humanitarian, and champion for mental health, Anna PATTY DUKE Pearce, closed her eyes, quieted her pain and ascended to a beautiful place," Astin wrote in a Facebook post on behalf of his family.
"We celebrate the infinite love and compassion she shared through her work and throughout her life. Her work endures..."
The post ended with a link to The Patty Duke Mental Health Project, for which he is raising money to support.