The 40-year-old actor -- who currently headlines the Brodway show Hedwig and the Angry Inch -- showcases the significant weight loss he underwent for the production in the cover. His husband David Burtka told Rolling Stone that Harris' new skinny physique "really gives him power."
Harris' interview for the magazine is titled "How He Met Himself," a play on the name of the CBS hit sitcom he co-starred in for nine years, How I Met Your Mother. In the cover story the actor discusses the impact that playing Lothario Barney Stinson on the show had in his life and how coming out helped his career.
He also talks about his character as Hedwig, a role that Burtka wasn't sure he could pull off because of the femininity of the character.
"This is such a stretch for him," Burtka said. "In his day-to-day, he's not a very feminine guy."
"I have always been highly aware of how I was presenting myself," Harris said. "Which, now that I'm playing overtly feminine and loving it, is kind of a stupid concern."
Rolling Stone's June issue featuring Harris on the cover hits stand Friday.
Celebrity Couples of 2014 [PHOTOS]