The 53-year-old actress recently posed naked for the magazine's upcoming April 24 issue. The star wore a large, fake back tattoo for the cover that appeared to be a transcription of the United States Constitution.
The tattoo's historical inaccuracy has since made history fans roll their eyes in exasperation. The text begins "We the People," like the U.S. Constitution, but is too short to be the actual document. In addition, John Hancock's signature appears on Louis-Dreyfus' lower back, but the statesman did not sign the Constitution.
Many have taken to Twitter or other social media to point out the mistake, and The National Constitution Center in Philadelphia has even chimed in.
Dreyfus herself has taken to Twitter to laugh about the mistake, referencing her character's staff on her HBO comedy series Veep.
"Hancock signed Dec. of Independence NOT Constitution," the actress writes. "Yet another Mike [expletive]-up. Dummy. #veep #crackexcuse @VeepHBO @mrmattwalsh cc@rollingstone."