Dunham, who appeared naked during the show in a skit about Adam and Eve, was called out on Twitter by a fan who claimed she doesn't "always have to get naked!" In return, Dunham tweeted: "Please tell that to my uncle, mister. He's been making me!"
After her joke prompted some bad reactions on the social media site, Dunham apologized to her over 1.45 million followers, explaining that she was "really sleepy" and that "even naked girls get embarrassed."
"I just made and deleted a not so great molestation joke. Sorry guys. I am really sleepy," Dunham wrote after deleting her molestation tweet.
"SNL has a way bigger audience than our usual cozy girls audience, so I was seeing a rash of very different kinds of twitter rage," she continued.
"But I should know better, and do. Even naked girls get embarrassed. Sleep well and thanks for an amazing weekend," Dunham concluded.
Dunham made her SNL debut Saturday; you can check out the skit that got her in trouble below.