The theft was discovered on Monday night when Khloe and her mom Kris visited the home to clean it out. The house, which Khloe shared with ex Lamar Odom, has been unoccupied for a month and was recently sold to Big Bang Theory star Kaley Cuoco.
Khloe reportedly suspects that the thief or thieves are people with direct access to the house -- house staff, assistants, filming crowds, inspectors, or movers. There was no sign of a break-in, and the house itself is gated and located inside a gated community.
Khloe is said to be demanding lie detector tests and fingerprints from every person who had access to the jewelry. Sources say that Khloe's estranged husband Lamar Odom is not a suspect, as he has been away in Spain playing basketball.
Celebrity Families of 2014 [PHOTOS]