Directed by Daniel Sullivan, and produced by Frederick Zollo and Robert Cole, this production will mark the first Broadway staging of the play.
"I have dreamed, for a long time, of doing this play with this director. It's an honor to work with Dan Sullivan in Lyle Kessler's 'Orphans,'" Baldwin said in a statement Wednesday.
"In the play, two orphaned brothers are living in a decrepit North Philadelphia row house. Treat, the eldest, supports his damaged younger sibling by petty thievery, and makes the house a virtual prison for the seemingly simple-minded Phillip," a synopsis said. "One night, he kidnaps a rich older man; Harold turns out to have his own motives and becomes the father figure the boys have always yearned for."
Baldwin is to play the role of Harold. The roles of Treat and Phillips are yet to be cast. The show will play at a Shubert Theatre to be announced, the producers said.
Baldwin's New York stage credits include "Entertaining Mr. Sloane," "Loot," "Prelude to a Kiss," "A Street Car Named Desire," "Macbeth" and "The Twentieth Century." He also appeared in the films "Beetlejuice," "Working Girl," "Miami Blues," "The Hunt for Red October," "Glengarry Glen Ross," "Malice," "The Juror," "The Edge," "Ghosts of Mississippi," "State and Main," "The Cat in the Hat," "The Cooler," "The Aviator," "The Departed" and "It's Complicated."