The newly discovered work, dated around 1500, will be exhibited for the first time in November, New York art historian and private dealer Robert Simon said in a news release Thursday.
One of 15 surviving da Vinci oil paintings, the piece was known, but presumed to have been destroyed. It will be included in "Leonardo da Vinci: Painter at the Court of Milan" at the National Gallery in London from Nov. 9 until Feb. 5, Simon said.
Called "Salvator Mundi" or "Savior of the World," the work depicts a half-length figure of Christ facing forward and holding a crystal orb in his left hand as he raises his right in blessing.
The "Salvator Mundi" is privately owned and not currently for sale, Simon said.