Swayze, the star of "Dirty Dancing" and "Ghost," died Monday of pancreatic cancer at the age of 57. He had made a guest appearance on "'Dancing with the Stars" in its first season.
In the tribute, the dancers will perform a three-song medley featuring Swayze's "She's Like the Wind," 'Unchained Melody" from the hit film "Ghost" and the classic "Time of My Life" from "Dirty Dancing," ABC said in a news release.
Wednesday's edition of the television dance competition series will also feature the elimination of Season 9's first two couples, as well as performances by Sean Kingston and the cast of Broadway's "The Lion King."
This season's celebrity contestants are Aaron Carter, Natalie Coughlin, Mark Dacascos, Tom De Lay, Macy Gray, Ashley Hamilton, Melissa Joan Hart, Kathy Ireland, Michael Irvin, Joanna Krupa, Chuck Liddell, Debi Mazar, Mya, Kelly Osbourne, Donny Osmond and Louie Vito.