Glau previously co-starred in "Terminator: The Sarah Connor Chronicles" and Whedon's "Firefly."
TVGuide.com said she will be featured in a few episodes during the second season of "Dollhouse."
Also to appear on the show are "Battlestar Galactica" veterans Jamie Bamber and Michael Hogan, and Alexis Denisof, who co-starred in Whedon's popular series "Buffy the Vampire Slayer" and "Angel," TVGuide.com noted.
Keith Carradine has been booked to play a recurring role next season, as well.
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