Zombie has signed on to write and direct the new horror flick, which will pick up at the exact moment the last movie stopped.
Malek Akkad of Trancas International Films, who also produced 2007's "Halloween" with Dimension, a division of The Weinstein Co., will produce the sequel, along with Andy Gould of Spectacle Entertainment Group, Zombie's long-time manager and producing partner.
The announcement was made Tuesday by Bob Weinstein, co-chairman of The Weinstein Co.
"Following the success of 2007's 'Halloween,' we are thrilled to be back in business with Rob Zombie, bringing a sequel to theaters," Weinstein said in a statement. "The fans have made it clear -- and we agree -- that they feel the franchise is in great hands with Rob Zombie."
"I am very excited to be working with Bob Weinstein again and returning to the world of 'Halloween.' The remake laid the groundwork, now it's time to really take Michael Myers to the next level. I believe we've just barely scratched the surface of where we can take this series," said Zombie.
John Carpenter's "Halloween" established the franchise in 1978.