The former "All My Children" co-stars wed 12 years ago and are the parents of three children.
"There is no truth to the story. Their marriage continues to be quite healthy and the National Enquirer should be ashamed for fabricating such an untruthful story," Ripa's spokesman Stan Rosenfield told People magazine Wednesday. "Their story is 100 percent false."
Celebrity Families of 2014 [PHOTOS]