Pastore is scheduled to perform in Louis LaRusso's stage play starting Friday at the Arclight Theatre in New York.
The show also stars Pastore's fellow "Sopranos" alumni Frank Pellegrino, Robert Funaro, Anthony Ribustello and Ricky Aiello. Aiello's actor father, Danny, starred in the original 1975 Broadway staging of "Lamp Post."
Pastore has designated the Nov. 17 performance as a fundraiser for The Lustgarten Foundation for Pancreatic Cancer Research, the organization said in a news release.
2014: The Year in Music [PHOTOS]