Kelly had a seven-day total of $222,597.
In addition to being the "winningest" female champion in the quiz show's 24 seasons, she also has become the third biggest money winner behind all-time "Jeopardy!" champ Ken Jennings, who went home with $2.5 million, and David Madden, who won $430,400, representatives for the series said.
"My husband and I have been grad students for awhile now, so it will definitely be nice to have a down payment on a house," Kelly said in a statement.
Kelly's husband Jeff appeared on the program in 2004 and her sister Arianna is scheduled to appear on the show July 8.
N.J. man wakes up from 10-hour sleep with knife in back
Puzzle-maker slips 'Murdoch Is Evil' into Rupert Murdoch's Sunday Telegraph