The movie is based on the book "Murder in Sin City" by Jeff German -- inspired by the true story of the death of wealthy Las Vegas casino heir Ted Binion and the ensuing trial of his lover and her con artist boyfriend.
The film is scheduled to premiere on Lifetime in September.
"Much like a trip to Vegas, this movie is a guilty pleasure," Tanya Lopez, senior vice president of Original Movies for Lifetime Networks, said in a statement. "Ripped from the headlines, 'Sex & Lies in Sin City' captures all of the true crime story elements and the madness that surrounded Ted Binion's life."
Suvari is best known for her roles in "American Beauty," and "American Pie."
Modine is an acting veteran with more than 50 films to his credit, including "Married to the Mob," "Full Metal Jacket" and "Any Given Sunday."