"Momma's Boys" will also be executive-produced by "Average Joe" co-creator Andrew Glassman.
NBC said the new series is set to premiere on the heels of "All-American Summer" and the "Summer Olympic Games in Beijing."
"Anytime I make a decision either personally or professionally, I have to ask myself ... what would my mother say? Like it or not, I am a true Momma's Boy," Seacrest said in a statement. "She is the most important woman in my life and she is never short of opinions. This series throws Mom right in the middle of all the drama. It's loud, it's wild and it's real. (Ryan Seacrest Productions) and NBC have developed a strong partnership that allows the opportunity to both promote and create original content across my already existing media platforms."
In describing the new show, NBC said: "Conflict results when numerous mothers and their eligible bachelor sons are housed together with several 'brides-to-be ...' Some of the possible brides are 'nice girls' -- while others might not be as appealing to the mothers."