Lohan has been cast as Nancy Pitman, who grew up wealthy in Malibu, met Manson when she was 16 and moved in with him shortly after.
She was home with Manson the night in 1969 when he instructed members of his group to go to the former residence of an ex-business associate where they killed actress Sharon Tate and four other people, E! noted.
Pitman, who also went by the name Brenda McCann, later got mixed up with the Aryan Brotherhood and served 18 months in prison after she was convicted of being an accessory after the fact to murder.
Celebrity Breakups and divorces of 2014 [PHOTOS]