"The reports about him being in rehab are wrong. Eddie is sober," Bertinelli told People.com Wednesday. "He's being proactive about his illness."
Bertinelli declined to offer any details regarding Van Halen's ailment or condition, however.
"I don't think it's my place (to comment,)" she told the magazine.
"I talk to him about every other day. He wants to get back on tour. I think they'll be back on the road by April 19."
The band announced on its Web site this week that it was temporarily suspending its tour because Van Halen is under doctors' care and undergoing tests.
The message said the band planned to resume its tour April 19 and would announce rescheduled dates shortly.
Bertinelli and Van Halen have a 16-year-old son, Wolfgang, who is touring with the band as its bassist.