The Thursday event will include an all-star line-up of comedians who embody the Seinfeld spirit, as well as an exhibit of Seinfeld memorabilia from the comedian's early days at the club.
Audience members will be invited to partake in a Seinfeld impression contest, the winner of which will be awarded free admission for life at the Comic Strip Live.
"You dream about the 9 o'clock spot on Saturday night at the Comic Strip Live," Seinfeld once told Liz Smith of the New York Post.
Seinfeld's new animated "Bee Movie" is now No. 1 at the box office.