Clapton headlined the show, hosting former Blind Faith bandmate and Traffic leader Steve Winwood and The Band's Robbie Robertson during his set and also jamming with Sonny Landreth and with a consortium of Sheryl Crow, Vince Gill and Albert Lee. Other performers included Jeff Beck, Buddy Guy, B.B. King, John Mayer, Willie Nelson and Alison Krauss & Union Station.
Comedian Bill Murray, a Chicago native, hosted the event, appearing in a series of costumes that mimicked Clapton's looks over the years.
The festival, a follow-up to Clapton's 2004 event in Dallas, raises money for Clapton's Crossroads Centre rehabilitation facility in Antigua.
Teacher apologizes for showing sexual image of herself in class
Dennis Rodman pledges to end trips to North Korea