David Tennant, who took over the lead role from Christopher Eccleston this season, was named most popular actor, his co-star Billie Piper won most popular actress and the long-running series itself was crowned most popular drama in the awards voted by the television audience.
The factual award went to the BBC's "Top Gear."
In accepting the award, Jeremy Clarkson said it would cheer up the entire "Top Gear" crew, which has had a "torrid time of it" since host Richard Hammond was seriously injured in a high speed crash while taping a segment of the show last month.
Channel 4 scored with "Deal or No Deal's" best daytime series win and its "Big Brother" chalked up its third consecutive reality TV prize, the BBC reported.
"EastEnders" repeated as the most popular serial drama, "Little Britain" won its third consecutive comedy award while Ant and Dec were voted favorite presenters for the fifth year in a row.
The biggest surprise was the dethroning of "Who Wants to be a Millionaire?," which had its seven-year run as favorite game show stopped by Ant and Dec's "Game Show Marathon."
The entire ceremony with Trevor McDonald as host was taped for broadcast Wednesday night on ITV1.