The show, "Rembrandt -- Quest of a Genius," features about one-sixth of his work in the four-story house where he lived from 1639 to 1658.
Ernst van de Wetering, head of the Rembrandt Research Project, said Rembrandt earned a good living as an artist, but died almost penniless in 1669 at the age of 63 because of his poor money management skills.
Van de Watering said Rembrandt painted his own self-portrait many times because they sold well, and not because he wanted to experiment.
The works are so different that "you can't believe it's the same person," he said.
Among the works are two recently discovered pieces from Warsaw, the Canadian Broadcasting Corp., reported. "Scholar at His Desk" and "Girl in a Picture Frame" are on view, as well as a painting of a maid in a white bonnet, auctioned off recently to a New York collector for $4.3 million.