"50 Cent has made a lot of money, but whatever you are doing that makes you have to put a bulletproof vest on your 5-year-old son, that's time for some deep introspective (expletive)," the "Malcolm X" director told Complex magazine.
Lee also said in the interview "young brothers" seriously subscribe to 50 Cent's "Get Rich or Die Tryin'" mantra, the New York Daily News reported Tuesday.
"For me, that's criminal," Lee tells Complex magazine. "Because young brothers, they took that to heart. (They're like, 'Whatever I got to do to get them rims, get my fly gear, to get my bitches and hos, I am going to do it. (Expletive) who I got to hurt, who I got to shoot, who I got to kill.' That's crazy to me."
Lee was also critical of the controversial posters for the 50 Cent movie, which showed the rapper carry firearms, the Daily News said.
NBC reportedly holds celebs hostage to Jimmy Fallon's show
Aaron Carter is still in love with Hilary Duff