The rapper will play songs from his soon-to-be released album, "Todd Smith" and let fans vote their favorite LL Cool J hits to fill out the rest of the show, AllHipHop.com reported.
The "LL Cool J Custom Concert Featuring Ne-Yo and Special Guest" will be taped March 3 and aired March 18 on the network owned and operated by women.
"We love LL Cool J because he is a hip-hop legend and a star with a huge female fan base," Oxygen's Julie Insogna said. "It is an honor to feature an artist who has not only been incredibly important to hip-hop and the music industry overall, but also appeals to women across generations."
Oxygen is available in about 66 million U.S. homes.
Notable deaths of 2014 [PHOTOS]
Kris and Bruce Jenner divorcing