The almost life-size painting of the supermodel reclining on a bed was done by Lucian Freud, grandson of the famed psychoanalyst and one of Britain's most respected artists. It expected to bring close to $6 million.
Freud began work on the painting in 2001 when he started sketching Moss early in her pregnancy.
The painting is scheduled for auction Wednesday.
Celebrity Families of 2014 [PHOTOS]