"('A Dirty Shame' is) about a town full of sexual deviants, and they battle the neuters for control of the town," Knoxville recently told reporters. "And I play the head sexual deviant."
Despite the "Jackass" star's own reputation for outrageous antics, Knoxville said he was surprised when Waters first approached him about the project.
"He invited me to lunch about two and a half years ago and said ... he's writing the character for me and would I be interested?" Knoxville recalled. "Then he pulled out all these fetish mags and goes, 'By the way -- this is what it's about.'"
An NC-17 rating means anyone age 17 and under will be denied admission.
"A Dirty Shame" is the third film this year to be rated NC-17.