Osmond, who had suffered for the past 5 1/2 years from numerous strokes, died Sunday surrounded by family, Salt Lake City's Deseret News reported Monday.
"They've been anticipating this, but nothing prepares you for the time, or (for) it to come on Mother's Day," family spokesman Ron Clark told the newspaper.
Osmond and her husband, George, were parents to nine children, with seven of them becoming successful performers.
The Osmonds Brothers garnered dozens of platinum and gold albums during the 1970s as one of music's biggest acts. Donny Osmond left his brothers for a successful solo career, as well as joining sister Marie for a TV variety show that lasted four seasons. The youngest, Jimmy, also performed.
Osmond is survived by her husband, nine children, 55 grandchildren and 22 great-grandchildren.