The 70-year-old is taking the lead, and husband Percy Gibson will work with her as stage manager, Sky News reports.
"This is the third time we have worked together. We get along brilliantly so I feel great about it," said the British actress, promoting the romantic comedy in London.
The five-times married sister of novelist Jackie Collins said she was no expert on men.
"Some of them are wonderful. Some of them are pretty horrible. You can't generalize about men just as you can't generalize about people," she said
The secret to a successful relationship, she said, was "just being each other's best friend, sharing everything, and being on the same wavelength.
"My husband and I started off as friends which has been very important for our relationship."
Full Circle opens on March 11 before taking off on a regional tour.