The star of "Charlie's Angels," "Boys on the Side" and "E.T. The Extra-Terrestrial" will get a star in front of the historic Grauman's Chinese Theatre on Hollywood Boulevard.
Barrymore's newest project -- the romantic comedy "50 First Dates" -- is scheduled to open Feb. 13. The picture re-teams her with Adam Sandler, her co-star in the 1993 comedy "The Wedding Singer."
Barrymore most recently co-starred with Ben Stiller in "Duplex." Her other screen credits include "Confessions of a Dangerous Mind," "Never Been Kissed," "Scream" and the Woody Allen comedy "Everyone Says I Love You."
Barrymore made her feature film debut in 1980, appearing in "Altered States" with William Hurt.
She is the fifth member of the famed Barrymore family to be honored with a star on the Hollywood Walk of Fame -- joining her famous relatives Ethel, John, John D. and Lionel Barrymore as recipients of the honor.