"From here on in, it will be new stuff, and we're in the active band cycle of album-tour-album-tour -- I hope forever," the artist told Billboard.com.
Fans can expect some surprises when the E Street Band returns to the States, beginning July 15 in East Rutherford, N.J.
Although he noted the band's current show is still based on last year's Columbia album, "The Rising," Van Zandt says, "It's a very different show than the one we started with."
On the road, Bruce Springsteen is continuing to prove "a master of spontaneity."
"The other night, he called out a song we haven't played in 18 years but that's the kind of thing that keep things fresh and interesting," he said.