• Old nuclear reactor avoids replacement
    Published: May 16, 2008 at 4:16 PM
    OTTAWA, May 16 (UPI) -- The world's oldest nuclear reactor won't be replaced due to budgetary and scheduling concerns, Atomic Energy of Canada Ltd. says.
  • U.S. markets closed mixed
    Published: May 16, 2008 at 4:16 PM
    NEW YORK, May 16 (UPI) -- U.S. market indexes closed mixed Friday as a wavering afternoon rally could not bring the Dow Jones index out of the doldrums.
  • Family and school stress linger for teens
    Published: May 16, 2008 at 4:12 PM
    LOS ANGELES, May 16 (UPI) -- Some teens may not do well in school because stress at home affects their academic performance and vice versa, U.S. researchers said.
  • Old nuclear reactor avoids replacement
    Published: May 16, 2008 at 4:16 PM
    OTTAWA, May 16 (UPI) -- The world's oldest nuclear reactor won't be replaced due to budgetary and scheduling concerns, Atomic Energy of Canada Ltd. says.
  • U.S. markets closed mixed
    Published: May 16, 2008 at 4:16 PM
    NEW YORK, May 16 (UPI) -- U.S. market indexes closed mixed Friday as a wavering afternoon rally could not bring the Dow Jones index out of the doldrums.
  • Family and school stress linger for teens
    Published: May 16, 2008 at 4:12 PM
    LOS ANGELES, May 16 (UPI) -- Some teens may not do well in school because stress at home affects their academic performance and vice versa, U.S. researchers said.
  • Canadian youth to face lighter sentencing
    Published: May 16, 2008 at 4:11 PM
    OTTAWA, May 16 (UPI) -- Young people in Canada convicted of violent crimes won't routinely face adult sentences in the future, the Supreme Court of Canada has ruled.
  • Cows stampede on California highway
    Published: May 16, 2008 at 4:07 PM
    CONCORD , Calif., May 16 (UPI) -- The California Highway Patrol said 10 cows wandered into traffic after they escaped from a trailer on Highway 4, near the interchange with Interstate 680.
  • Crime rate among Canadian young rising
    Published: May 16, 2008 at 4:07 PM
    TORONTO, May 16 (UPI) -- The crime rate among Canadian residents ages 12 to 17 increased by 3 percent from 2005 to 2006, a study has found.

Autism risk factor linked to moms, age


Published: July 26, 2007 at 4:48 PM
COLD SPRING HARBOR, N.Y., July 26 (UPI) -- Autism, a developmental disorder, may more likely be carried by mothers and dependent on parental age, according to U.S. researchers.

Researchers at Cold Spring Harbor Laboratory and Albert Einstein College of Medicine analyzing the incidence of autism found a previously unrecognized pattern pointing to a spontaneous germ-line mutation model of disease acquisition.

The study, published in the Proceedings of the National Academy of Sciences, indicates parents, especially women -- who acquire the mutation but do not exhibit severe symptoms of the disorder -- have a 50 percent chance of passing the mutation on to their children. Sons often show the most severe symptoms.

"The fact that germ-line mutations increase with age places older parents at a higher risk of having children with autism, explaining a pattern that has been recently observed," study co-author Michael Wigler, of CSHL, said in a statement.

The model proposes two risk classes. One is sporadic or low risk autism -- the more common form -- caused by spontaneous germ-line mutation. The children, mostly female, who receive such a mutation but do not display the disorder, are the source of the other risk class -- high risk families. Boys in high risk families may account for a quarter of autism. according to the study.


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