ATLANTA, March 28 (UPI) -- New U.S. guidelines recommend women with an increased risk of breast cancer receive magnetic resonance imaging screening in addition to mammography.
An expert panel convened by the American Cancer Society formed the new recommendations. Annual screening using MRI is suggested for women who have:
-- A BRCA 1 or 2 mutation.
-- A lifetime risk of breast cancer of 20 percent to 25 percent or more using standard risk assessment models.
-- Received radiation treatment to the chest between 10 and 30.
-- A first-degree relative who carries a genetic mutation in the TP53 or PTEN genes, which are Li-Fraumeni syndrome and Cowden and Bannayan-Riley-Ruvalcaba syndromes.
The panel also identified several risk subgroups for which the available data are insufficient to recommend for or against MRI screening. Those include:
-- Women with a personal history of breast cancer.
-- Carcinoma in situ.
-- Atypical hyperplasia.
-- Extremely dense breasts on mammography.
The complete guidelines are published in the March/April issue of CA: A Cancer Journal for Clinicians.
