The New York Federal Reserve said its monthly business index came in at minus 7.8, below the consensus forecast that called for a rise to the break-even point of zero.
By close of trading on Wall Street, the Dow Jones industrial average added 27.57 points or 0.2 percent to 13,534.89. The Nasdaq composite index shed 6.72 points or 0.22 percent to 3,110.78. The Standard and Poor's 500 gained 1.68 points or 0.11 percent to 1,472.34.
On the New York Stock Exchange, 1,740 stocks advanced and 1,291 declined on a volume of 3.1 billion shares traded.
The 10-year treasury note rose 3/32 to yield 1.84 percent.
Against the dollar, the euro fell to $1.33 from Monday's $1.3382. The dollar was lower at 88.77 yen from 89.48 yen.
In Tokyo, the Nikkei 225 index added 0.72 percent, 77.51 points, to 10,879.08.
In London, the FTSE 100 index added 0.15 percent, 9.45 points, to 6,117.31.